Predictive factors of amoxicillin immediate hypersensitivity and validation of PEN-FAST clinical decision rule

CONCLUSION: PEN-FAST has been validated to identify low-risk penicillin allergies in our European cohort of patients mainly reporting anaphylaxis. This is the first reported external validation of a penicillin allergy clinical decision rule internationally.AUTHOR CONTRIBUTIONS: Concept and design: Piotin, de Blay, Metz-Favre. Acquisition, analysis, or interpretation of data: All authors.Drafting of the manuscript: Piotin, de Blay, Metz-Favre. Critical revision of the manuscript for important intellectual content: All authors.CONFLICTS OF INTEREST: All authors except Frédéric de Blay have no conflict of interest. Frédéric de Blay perceived financial support: Clinical Grants (Aimmune, Stallergènes-Greer, ALK, Novartis, AstraZeneca, DBV, Sanofi, GSK), board membership (Aimmune, Stallergènes Greer, ALK, Novartis, AstraZeneca, DBV, Sanofi).FUNDING SOURCE: none.PMID:34271183 | DOI:10.1016/j.anai.2021.07.005
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research