Superior cellular and humoral immunity toward SARS-CoV-2 reference and alpha and beta VOC strains in COVID-19 convalescent as compared to the prime boost BNT162b2 vaccinated dialysis patients

Patients undergoing maintenance dialysis (DP) have a high risk of fatal coronavirus disease 2019 (COVID-19).1 Recent epidemiological data raise apprehension with respect to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) for DP.2,3 Therefore, ensuring cellular and humoral immunity directed to SARS-CoV-2 including VOC isolates is essential for this population. There are no data on vaccine-induced nor on natural SARS-CoV-2 infection –induced long-term immunity and its responsiveness to VOC isolates in DP.

Source: Kidney International - July 13, 2021 Category: Urology & Nephrology Authors: Arturo Blazquez-Navarro, Lema Safi, Toni L. Meister, Constantin J. Thieme, Sviatlana Kaliszczyk, Krystallenia Paniskaki, Mara Stockhausen, Jan H örstrup, Okan Cinkilic, Linus Flitsch-Kiefner, Corinna Marheinecke, Eike Steinmann, Felix S. Seibert, Ulrik S Tags: Letter to the Editor Source Type: research