17,18-Epoxyeicosatetraenoic Acid Inhibits TNF- α-Induced Inflammation in Cultured Human Airway Epithelium and LPS-Induced Murine Airway Inflammation

CONCLUSION: These results indicate that 17,18-EpETE plays a regulatory role in mucus hypersecretion and neutrophil infiltration in nasal inflammation. Local or systemic administration may provide a new therapeutic approach for the treatment of intractable airway disease such as CRS.PMID:34236247 | DOI:10.1177/19458924211027682
Source: American Journal of Rhinology and Allergy - Category: ENT & OMF Authors: Source Type: research