A radiomic signature model to predict the chemoradiation-induced alteration in tumor-infiltrating CD8 < sup > + < /sup > cells in locally advanced rectal cancer

CONCLUSION: We established the MRI-derived radiomic signature for predicting CRT-induced alterations in CD8+ TILs. This study suggests the clinical utility of radiomics-immunophenotype modeling to evaluate tumor immune status following neoadjuvant chemoradiation in rectal cancer.PMID:34265357 | DOI:10.1016/j.radonc.2021.07.004

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - July 15, 2021 Category: Radiology Authors: Seung Hyuck Jeon Yu Jin Lim Jaemoon Koh Won Ick Chang Sehui Kim Kyubo Kim Eui Kyu Chie Source Type: research