Temporal correlation of morphological and biochemical changes with the recruitment of different mechanisms of reactive oxygen species formation during human SW872 cell adipogenic differentiation
In conclusion, the morphological and biochemical changes of differentiating SW872 cells are accompanied by the discontinuous formation of ROS derived from NOX-2, increasingly implicated in adipogenesis and adipose tissue dysfunction. In addition, mROS formation was significant only in the late phase of differentiation and was associated with mitochondrial dysfunction.
Source: BioFactors - Category: Biochemistry Authors: Mara Fiorani,
Rita De Matteis,
Barbara Canonico,
Giulia Blandino,
Alessandro Mazzoli,
Mariele Montanari,
Andrea Guidarelli,
Orazio Cantoni Tags: Research Communication Source Type: research