Simple metabolic markers associated with tophaceous gout

ConclusionsUA, eGFR, γ-GT and ALT were independently associated with tophi. The γ-GT/ALT ratio may be used as a predictor or monitor of tophi.Key Points•We found that UA, eGFR, γ-GT and ALT were independently related to tophi among clinical commonly indicators.•The γ-GT/ALT ratio performed best in the identification of tophaceous gout from gout.•The incidence of tophi and chronic kidney disease and duration of hyperuricemia increased with γ-GT/ALT ratio.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research