Unraveling the role of liver sinusoidal endothelial cells in COVID-19 liver injury

Liver injury is common during SARS-CoV-2 infection. Abnormalities in liver tests can be found in up to 50% of infected patients [1]. In most cases, COVID-19 liver test perturbations consist mainly in liver aminotransferase elevation and correlate with disease severity defined as ICU admission and mortality [2, 3]. Liver injury is generally mild and does not lead to liver failure in patients without advanced liver disease. Patients with decompensated cirrhosis, however, have a significant risk of develop acute-on-chronic liver failure [4].
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Editorial Source Type: research