Long-term weight gain after initiating combination antiretroviral therapy in treatment-na ïve Asian people living with human immunodeficiency virus

The development of antiretroviral therapy (ART) has substantially improved the morbidity and mortality of people living with human immunodeficiency virus (PLWH) (Samji et al. 2013; Oka et al. 2020). With an increase in the life expectancy of PLWH, long-term complications of ART have also been highlighted. PLWH gain weight after starting ART, owing to the “return to health” effect or adverse effects from the therapeutic drugs (Kumar and Samaras 2018). Such weight gain increases the chances of PLWH being overweight and obese; this leads to complications such as cardiovascular diseases, diabetes mellitus, and neurocognitive impairment (Butt et al.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research