Hemophagocytic Lymphohistiocytosis in Adult and Pediatric Patients: Perspectives from a Tertiary Care Center
Hemophagocytic lymphohistiocytosis (HLH) describes a group of syndromes associated with immune system overstimulation.1 These syndromes can be divided into primary/familial and secondary/reactive.1 Primary HLH results from genetic mutations, while secondary HLH is attributed to viral infection, malignancy or autoimmune condition.1 Diagnosis and management is based on HLH-2004, the most widely used diagnostic criteria of HLH.2 Our study reviews adult and pediatric patients with HLH at our institution to improve understanding of this condition.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Minh H.N. Nguyen, Melissa Baker, Tahnee Spoden, Maritza Gisel Rivera-Valenzuela, Roua Azmeh Source Type: research
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