|Isolation and characterization of novel bacteriophages as a potential therapeutic option for Escherichia coli urinary tract infections

In conclusion, these novel phages showed the ability to decrease biofilm and bacterial adherence, making them promising candidates for effective adjuvant treatment against UTIs caused by MDR UPEC strains. KEY POINTS: Phage with lytic activity against MDR UPEC strains were isolated and characterized under in vitro conditions. A novel method was proposed to evaluate phage activity against bacterial adherence in HEp-2 cell.. Phages represent a suitable strategy to control infections caused by MDR bacteria.PMID:34254156 | DOI:10.1007/s00253-021-11432-6
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Source Type: research