Quantum physics helps destroy cancer cells

(Kyoto University) Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles. The iodine releases electrons that break the tumor's DNA, leading to cell death. The findings, by scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan and the US, were published in the journal Scientific Reports.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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CONCLUSIONS: AXB algorithm yields more accurate dose prediction than AAA in heterogeneous medium. Differences in dose distribution are observed when plans re-calculated with AXB indicating that AAA apparently overestimates dose, particularly the PTV dose. Thus, AXB algorithm should be used in preference to AAA for cases in which PTVs are involved with tissues of highly different densities, such as lung.PMID:34542053 | DOI:10.3233/XST-210942
Source: Journal of X-Ray Science and Technology - Category: Radiology Authors: Source Type: research
Conclusions: It is reasonable to expect that use of methylproamine analogues will help to ascertain the relative contributions of the high-LET effects (not protected), compared to other components, including bystander effects, that are subject to radioprotection. This could be a useful tool in evaluating Auger endoradiotherapy strategies.PMID:34519610 | DOI:10.1080/09553002.2021.1976862
Source: International Journal of Radiation Biology - Category: Radiology Authors: Source Type: research
CONCLUSIONS: MRI is more effective than US in diagnosing and assessing cervical lymph node metastases of papillary thyroid cancer.PMID:34511478 | DOI:10.3233/XST-210927
Source: Journal of X-Ray Science and Technology - Category: Radiology Authors: Source Type: research
ConclusionThe 75th percentile ESD was the highest compared to the American College of Radiology –American Association of Physicists in Medicine–Society for Pediatric Radiology (ACR–AAPM–SPR), European Commission (EC) and United Kingdom (UK) reports. Comparison of both methods for assessing ESD was within 40% as compared to other studies. Based on the above results, the indirect method can be implemented for clinical dose audit.
Source: Japanese Journal of Radiology - Category: Radiology Source Type: research
Chembiochem. 2021 Aug 18. doi: 10.1002/cbic.202100373. Online ahead of print.ABSTRACTChemotherapy is the primary treatment modality employed in the clinic for the treatment of cancer. Despite proven clinical success, adverse side effects are one of the drawbacks of this approach. The prodrug strategy has emerged as an alternative approach with the aim of alleviating these drawbacks. Prodrug activation is typically achieved by either endogenous or exogenous triggers. Exogenous triggers like light are appealing as they are independent of inherent patient and/or cancer type variations. However, tissue penetration depth remain...
Source: Chembiochem - Category: Biochemistry Authors: Source Type: research
To convince physicians and nurses that deep learning algorithms are worth using in everyday practice, developers need to explain how they work in plain clinical English.Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, and John Halamka, M.D., president, Mayo Clinic Platform, wrote this article.AI ’s so-called black box refers to the fact that much of the underlying technology behind machine learning-enhanced algorithms isprobability/statistics without a human readable explanation.Oftentimes that ’s the case because the advanced math or the data science behind the algorit...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
CONCLUSIONS: A community pharmacy referral service for lung symptoms was considered an acceptable alternative pathway to symptomatic diagnosis of lung cancer in deprived communities. Wider implementation of the service would require workforce capacity and training to be addressed to ensure optimum utilisation and promotion of the service.PMID:34376398 | DOI:10.1136/bmjresp-2020-000772
Source: Respiratory Care - Category: Respiratory Medicine Authors: Source Type: research
AbstractPhotobiomodulation-based (PBM-based) therapies show promising results in mucositis and dermatitis treatment by stimulating wound healing mechanisms such as cell proliferation and migration. The aim of the present study is to investigate the in vitro effects of CareMin650 on the proliferation and migration of two different types of cells, namely cancer and non-cancer cells, with or without X-ray radiation. Study design used PBM through a combination of 0-3-6 J/cm2 doses —with or without X-ray radiation—on the proliferation and migration capabilities of a keratinocyte cell line (HaCaT) and a squamous cell...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
J Xray Sci Technol. 2021 Aug 4. doi: 10.3233/XST-210906. Online ahead of print.ABSTRACTReducing X-ray radiation is beneficial for reducing the risk of cancer in patients. There are two main approaches for achieving this goal namely, one is to reduce the X-ray current, and another is to apply sparse-view protocols to do image scanning and projections. However, these techniques usually lead to degradation of the reconstructed image quality, resulting in excessive noise and severe edge artifacts, which seriously affect the diagnosis result. In order to overcome such limitation, this study proposes and tests an algorithm based...
Source: Journal of X-Ray Science and Technology - Category: Radiology Authors: Source Type: research
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