A stop-gain mutation in sigma factor SigH (MAB_3543c) may be associated with tigecycline resistance in < em > Mycobacteroides abscessus < /em >

Conclusion. The MAB_3543c mutation may represent a novel determinant of tigecycline resistance in M. abscessus. The findings of this study will hopefully contribute to our knowledge of potential tigecycline resistance mechanisms in M. abscessus, which may lead to better diagnostics and treatment modalities in the future.PMID:34236301 | DOI:10.1099/jmm.0.001378
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research