A new diterpenoid alkaloid from < em > Delphinium gyalanum < /em > C. Marquand & amp; Airy Shaw

Nat Prod Res. 2021 Jul 9:1-6. doi: 10.1080/14786419.2021.1948043. Online ahead of print.ABSTRACTA new C19-diterpenoid alkaloid named gyalanutine A (1) and fourteen known compounds 2-15 were isolated from the plant of Delphinium gyalanum C. Marquand & Airy Shaw. Compound 1 displayed an unusual lycoctonine-type C19-diterpenoid alkaloid skeleton with the cleavage of N-C19 and C7-C17 bonds, and the construction of the N-C7 bond. Structures were identified by multiple spectroscopic analyses including 1 D, 2 D NMR, IR and HR-ESI-MS. Compounds were tested for acetylcholinesterase inhibitory and anti-inflammatory activity.PMID:34241556 | DOI:10.1080/14786419.2021.1948043
Source: Natural Product Research - Category: Biochemistry Authors: Source Type: research
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