Nutrition and management of glycemia in neonates with neonatal encephalopathy treated with hypothermia

Adequate nutrition and glycemic homeostasis are increasingly recognized as potentially neuroprotective for the developing brain. In the context of hypoxia-ischemia, evidence is scarce regarding optimal nutritional support and administration route, as well as the short- and long-term consequences of such interventions. In this review, we summarize current knowledge on disturbances of brain metabolism of glucose and substrates by hypoxia-ischemia, and compound effects of these mechanisms on brain injury characterized by specific patterns on EEG and MRI.

Source: Seminars in Fetal and Neonatal Medicine - July 12, 2021 Category: Perinatology & Neonatology Authors: Pinchefsky EF, Schneider J, Basu S, Tam EWY, Gale C, Newborn Brain Society Guidelines and Publications Committee* Source Type: research