Associations between KCNQ1 and ITIH4 gene polymorphisms and infant weight gain in early life

CONCLUSIONS: Obesity-related loci rs2535633 and rs2237892 are associated with infant RWG in the first 3 months of infancy. The relationship between rs2237892 and infant RGW might be moderated by cesarean delivery.IMPACT: Genetic predisposition is an essential aspect to understand infant weight gain. Obesity-related SNPs, rs2535633 and rs2237892, are associated with RWG in very early years of life. The negative association between rs2237892 T allele and RWG is only observed in infants delivered vaginally instead of cesarean section.PMID:34247200 | DOI:10.1038/s41390-021-01601-8

Source: Pediatric Research - July 11, 2021 Category: Pediatrics Authors: Yuanyuan Zhang Hong Mei Ke Xu Chunan Li Ruixia Chang Haiqin Qi Ya Zhang Jianduan Zhang Source Type: research