Spatially-resolved pharmacokinetic/pharmacodynamic modelling of bystander effects of a nitrochloromethylbenzindoline hypoxia-activated prodrug
ConclusionsThe nitroCBI HAP SN30548 generates a highly efficient bystander effect through local diffusion of its active metabolite in tumour tissue.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
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