Hepatitis B Virus Monitoring Needed After Liver Transplantation

FRIDAY, July 9, 2021 -- Health care providers should test liver recipients for hepatitis B virus (HBV) given the slight risk for unexpected donor-derived HBV infection, according to research published in the July 9 issue of the U.S. Centers for...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Conclusions: TDF therapy is associated with a significantly lower risk of HCC recurrence, especially of late recurrence, than ETV therapy among patients who undergo curative hepatectomy for HBV-related early-stage HCC.Liver Cancer
Source: Liver Cancer - Category: Cancer & Oncology Source Type: research
Objectives: The aim of this study was to assess the 1-year safety and effectiveness of HBV Nucleic Acid Test positive (HBV NAT+) allografts in seronegative kidney transplant (KT) and liver transplant (LT) recipients. Summary Background Data: Despite an ongoing organ shortage, the utilization of HBV NAT+ allografts into seronegative recipients has not been investigated. Methods: From January 2017 to October 2020, a prospective cohort study was conducted among consecutive KT and LT recipients at a single institution. Primary endpoints were post-transplant HBV viremia, graft and patient survival. Results:...
Source: Annals of Surgery - Category: Surgery Tags: PAPERS OF THE 141ST ASA ANNUAL MEETING Source Type: research
CONCLUSIONS: The anti-HBc-positive graft itself does not affect patient survival or graft survival. HBIG monoprophylaxis has good outcomes for preventing DNH, and the patient's long-term cost burden can be low in Korea considering the insurance system in this cohort.PMID:34492755 | DOI:10.3350/cmh.2021.0137
Source: Clinical and molecular hepatology - Category: Gastroenterology Authors: Source Type: research
Source: Clinical Liver Disease - Category: Gastroenterology Authors: Tags: Review Source Type: research
World J Gastroenterol. 2021 Aug 7;27(29):4831-4845. doi: 10.3748/wjg.v27.i29.4831.ABSTRACTChronic infections with the hepatitis B and C viruses have significant worldwide health and economic impacts. Previous treatments for hepatitis C such as interferon and ribavirin therapy were ineffective and poorly tolerated by patients. The introduction of directly acting curative antiviral therapy for hepatitis C and the wider use of nucleos(t)ide analogues for suppression of chronic Hepatitis B infection have resulted in many positive developments. Decreasing the prevalence of hepatitis B and C have concurrently reduced transmissio...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Aug 7;27(29):4784-4801. doi: 10.3748/wjg.v27.i29.4784.ABSTRACTChronic infection with hepatitis B virus (HBV) remains a global health concern despite the availability of vaccines. To date, the development of effective treatments has been severely hampered by the lack of reliable, reproducible, and scalable in vitro modeling systems that precisely recapitulate the virus life cycle and represent virus-host interactions. With the progressive understanding of liver organogenesis mechanisms, the development of human induced pluripotent stem cell (iPSC)-derived hepatic sources and stromal cellular comp...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Aug 7;27(29):4831-4845. doi: 10.3748/wjg.v27.i29.4831.ABSTRACTChronic infections with the hepatitis B and C viruses have significant worldwide health and economic impacts. Previous treatments for hepatitis C such as interferon and ribavirin therapy were ineffective and poorly tolerated by patients. The introduction of directly acting curative antiviral therapy for hepatitis C and the wider use of nucleos(t)ide analogues for suppression of chronic Hepatitis B infection have resulted in many positive developments. Decreasing the prevalence of hepatitis B and C have concurrently reduced transmissio...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Aug 7;27(29):4784-4801. doi: 10.3748/wjg.v27.i29.4784.ABSTRACTChronic infection with hepatitis B virus (HBV) remains a global health concern despite the availability of vaccines. To date, the development of effective treatments has been severely hampered by the lack of reliable, reproducible, and scalable in vitro modeling systems that precisely recapitulate the virus life cycle and represent virus-host interactions. With the progressive understanding of liver organogenesis mechanisms, the development of human induced pluripotent stem cell (iPSC)-derived hepatic sources and stromal cellular comp...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Aug 7;27(29):4831-4845. doi: 10.3748/wjg.v27.i29.4831.ABSTRACTChronic infections with the hepatitis B and C viruses have significant worldwide health and economic impacts. Previous treatments for hepatitis C such as interferon and ribavirin therapy were ineffective and poorly tolerated by patients. The introduction of directly acting curative antiviral therapy for hepatitis C and the wider use of nucleos(t)ide analogues for suppression of chronic Hepatitis B infection have resulted in many positive developments. Decreasing the prevalence of hepatitis B and C have concurrently reduced transmissio...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Aug 7;27(29):4784-4801. doi: 10.3748/wjg.v27.i29.4784.ABSTRACTChronic infection with hepatitis B virus (HBV) remains a global health concern despite the availability of vaccines. To date, the development of effective treatments has been severely hampered by the lack of reliable, reproducible, and scalable in vitro modeling systems that precisely recapitulate the virus life cycle and represent virus-host interactions. With the progressive understanding of liver organogenesis mechanisms, the development of human induced pluripotent stem cell (iPSC)-derived hepatic sources and stromal cellular comp...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
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