Detection of pre-existing SARS-CoV-2-reactive T cells in unexposed renal transplant patients

CONCLUSIONS: This study shows that the magnitude and functionality of pre-existing SARS-CoV-2 reactive T cell in transplant patients is non-inferior compared to the immune competent cohort. Although several pro-inflammatory cytokines were produced by the detected T cells, further studies are required to prove their antiviral protection.PMID:34228322 | PMC:PMC8259083 | DOI:10.1007/s40620-021-01092-0

Source: Journal of Nephrology - July 6, 2021 Category: Urology & Nephrology Authors: Moritz Anft Arturo Blazquez-Navarro Ulrik Stervbo Sarah Skrzypczyk Oliver Witzke Rainer Wirth Mira Choi Christian Hugo Petra Reinke Toni Luise Meister Eike Steinmann Stephanie Pfaender Peter Schenker Richard Viebahn Timm H Westhoff Nina Babel Source Type: research