Plasma IL-12/IFN- γ axis predicts cognitive trajectories in cognitively unimpaired older adults

DISCUSSION: Immune dysregulation is implicated in early-stage cognitive decline, and greater IL-12/IFN-γ axis activation may be protective against cognitive decline and early-stage AD progression.PMID:34160128 | DOI:10.1002/alz.12399

Source: The Journal of Alzheimers Association - June 23, 2021 Category: Psychiatry Authors: Hyun-Sik Yang Can Zhang Becky C Carlyle Sherri Y Zhen Bianca A Trombetta Aaron P Schultz Jeremy J Pruzin Colleen D Fitzpatrick Wai-Ying W Yau Dylan R Kirn Dorene M Rentz Steven E Arnold Keith A Johnson Reisa A Sperling Jasmeer P Chhatwal Rudolph E Tanzi Source Type: research