Application of the modified cytosine base-editing in the cultured cells of bama minipig
This study provides a foundation for further application of somatic cell cloning to construct MSTN-edited Bama minipigs that carry only a single-base mutation and avoids biosafety risks to a large extent, thereby providing experience and a reference for the base editing of other genetic loci in Bama minipigs.PMID:34189671 | DOI:10.1007/s10529-021-03159-1
Source: Biotechnology Letters - Category: Biotechnology Authors: Jia-Sheng Pan Zi-Sheng Lin Jian-Cong Wen Jian-Feng Guo Xia-Hui Wu Ying-Ying Liu Wen-Jun Lai Qi-Ying Liang Yong-Shi Xie Yi-Rou Chen Yi-Hong Chen Ai-Fen Yan Juan Feng Lian Liu Dao-Yuan Gong Xiang-Xing Zhu Jia-Hong Lu Dong-Sheng Tang Source Type: research