Safety assessment of subtilisin QK in rats

CONCLUSION: The results showed that oral consumption of subtilisin QK is of low toxicological concern. No adverse effects were observed at doses of 2500, 7500, and 25,000 FU/kg in the 28-day subchronic toxicity, and the no-observed-adverse-effect level (NOAEL) of subtilisin QK was 25,000 FU/kg.PMID:34172094 | PMC:PMC8235616 | DOI:10.1186/s40360-021-00506-w

Source: BMC Pharmacology and Toxicology - June 26, 2021 Category: Drugs & Pharmacology Authors: Shuai Xiao Dingbang Hu Ya Gao Yang Ai Sang Luo Song Chen Ben Wang Li Zhou Yanshan Dong Yefu Wang Source Type: research