Role of LRP10 in Parkinson ’s disease in a Taiwanese cohort

Variants in the low-density lipoprotein receptor –related protein 10 (LRP10), linked to inherited forms of α-synucleinopathies, have been reported. Nine variants of LRP10 were identified in the first such report, and subsequent studies have identified possible pathogenic variants in patients with sporadic Parkinson’s disease (PD). Few studies have investigated the role of LRP10 in PD. We sought to validate the role of this gene in Taiwanese patients with PD.

Source: Parkinsonism and Related Disorders - July 1, 2021 Category: Neurology Authors: Ting-Wei Liao, Chun-Chieh Wang, Wen-Hung Chung, Shih-Chi Su, Szu-Han Chin, Hon Chung Fung, Yih-Ru Wu Source Type: research