Reply

We appreciate the commentary by Arisaka et  al and agree that there is a need to clarify relationships between insulin resistance and body mass index (BMI) in “early maturers.” Although Arisaka et al mention the importance of clarifying these relationships specifically in terms of sex differences, we believe it is equally important to consider race/ethnicity differences as well. Indeed, numerous studies have shown that insulin resistance differs by race/ethnicity. For example, Haffner et al found that nondiabetic non-Hispanic Blacks (NHBs) and Hispanics have increased insulin resistance and higher acute insulin response compared with nondiabetic non-Hispanic whites (NHWs).

Source: The Journal of Pediatrics - June 12, 2021 Category: Pediatrics Authors: Eric Morris Bomberg, Oppong Yaw Addo, Kyriakie Sarafoglou, Bradley Scott Miller Tags: Letters to the Editor Source Type: research