Comprehensive assessment of the effect of eye plaque tilt on tumor dosimetry

PURPOSE: Tilting of the posterior plaque margin during eye plaque brachytherapy can lead to tumor underdosing and increased risk of local recurrence. We performed a quantitative analysis of the dosimetric effects of plaque tilt as a function of tumor position, basal dimension, height and plaque type using 3D treatment planning software.MATERIALS AND METHODS: Posterior and anterior tumors with largest basal dimensions of 6, 12 and 18 mm and heights of 4, 7 and 10 mm were modeled. Both Eye Physics and COMS plaques were simulated and uniformly loaded.

Source: Brachytherapy - June 28, 2021 Category: Cancer & Oncology Authors: Matthew T. Studenski, Arnold Markoe, Stuart E. Samuels, Zelia M. Correa, Elizabeth Bossart, J. William Harbour Source Type: research