Non-communicable diseases of prematurity: time for a new mindset?

Jobe and Bancalari provide a paradigm shifting overview of BPD that highlights the futility of definitions based on disease severity and points out the “systemic” nature of such a disease during a lifetime trajectory(1). Jobe and Bancalari, who are two leading contributors to the history of BPD and research in this field, discuss the challenge of using the current definition of BPD to categorize longitudinal lung growth and function. Indeed, ve ry preterm subjects can develop some extent of lung functional impairment even in the absence of a BPD diagnosis and are placed on a trajectory of low lung function with a risk of developing a COPD-like phenotype in later life(2).
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Letters to the Editor Source Type: research