Newly discovered sperm movement could help diagnose, treat male infertility

(University of Toledo) The research finds that the atypical centriole in the sperm neck acts as a transmission system that controls twitching in the head of the sperm, mechanically synchronizing the sperm tail movement to the new head movement.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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CONCLUSIONS: These HFD-induced increases in pro-inflammatory cytokine expression levels and NF-κB and MAPKs signaling pathway activation in reproductive organs support the notion that increases of adipocytes resident and inflammatory status are symptomatic of female fertility impairment in obese mice.PMID:34560886 | DOI:10.1186/s12958-021-00833-x
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Source Type: research
Myomas can cause infertility depending on their size and site (1, 2). The International Federation of Gynecology and Obstetrics (FIGO) classification takes into account the degree of intramural extension and distortion of the uterine cavity (3). There are numerous mechanisms (Fig.  1) linking uterine fibroids and infertility (2): uterine cavity distortion (myoma types 0, 1, 2, 2–5); impaired endometrial and myometrial blood supply; greater uterine contractility; hormonal, paracrine, and molecular modifications; defective endometrial receptivity and gene expression, role of transforming growth factor beta-3 (TGF-...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Fertile battle Source Type: research
To develop a new endometriosis classification system for scoring intraoperative surgical complexity and to examine its correlation with patient-reported pain and infertility.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
The purpose of this American Society for Reproductive Medicine Practice Committee report is to provide clinicians with principles and strategies for the evaluation and treatment of couples with infertility associated with obesity. This revised document replaces the Practice Committee document titled “Obesity and reproduction: an educational bulletin” last published in 2015 (Fertil Steril 2015;104:1116–26).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: ASRM pages Source Type: research
Condition:   Infertility Intervention:   Other: cycles Sponsor:   Women's Hospital School Of Medicine Zhejiang University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Quality of Life Intervention:   Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Infertility Intervention:   Other: cycles Sponsor:   Women's Hospital School Of Medicine Zhejiang University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Quality of Life Intervention:   Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Expert Rev Mol Diagn. 2021 Sep 23. doi: 10.1080/14737159.2021.1985469. Online ahead of print.ABSTRACTINTRODUCTION: Infertility is a major health problem, worldwide, which affects 10-15% of couples. About half percent of infertility cases are related to male-related factors. Male infertility is a complex disease that is the result of various insults as lifestyle issues, genetics, and epigenetic factors. Idiopathic infertility is responsible for 30% of total cases. The genetic factors responsible for male infertility include chromosomal abnormalities, deletions of chromosome Y, and mutations and genetic variations of key gen...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Authors: Source Type: research
Environ Sci Pollut Res Int. 2021 Sep 24. doi: 10.1007/s11356-021-16581-9. Online ahead of print.ABSTRACTUntainted environment promotes health, but the last few decades experienced steep upsurge in environmental contaminants posing detrimental physiological impact. The responsible factors mainly include the exponential growth of human population, havoc rise in industrialization, poorly planned urbanization, and slapdash environment management. Environmental degradation can increase the likelihood of human exposure to heavy metals, resulting in health consequences such as reproductive problems. As a result, research into met...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Source Type: research
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