Evolution Over Time of Ventilatory Management and Outcome of Patients With Neurologic Disease*
OBJECTIVES:
To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality.
DESIGN:
Secondary analysis of three prospective, observational, multicenter studies.
SETTING:
Cohort studies conducted in 2004, 2010, and 2016.
PATIENTS:
Adult patients who received mechanical ventilation for more than 12 hours.
INTERVENTIONS:
None.
MEASUREMENTS AND MAIN RESULTS:
Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical Investigations Source Type: research