The complex interplay of cortex, cerebellum and age in a cohort of pediatric patients with tuberous sclerosis complex.

The neurodevelopmental impairment in tuberous sclerosis has a multifactorial origin. Various factors have been proposed as predictors of neurological outcome such as tuber load, early seizure onset and TSC2 mutation. Cerebellar lesions have been associated with worse neuroradiological phenotype but its contribution to the clinical phenotype is not well understood.

Source: Pediatric Neurology - June 25, 2021 Category: Neurology Authors: Christina Sidira, Efthymia Vargiami, Athanasia Anastasiou, Persefoni Talimtzi, Maria Kyriazi, Pinelopi Dragoumi, Maria Spanou, Argirios Ntinopoulos, Efterpi Dalpa, Athanasios Evangeliou, Dimitrios I. Zafeiriou Tags: Research Paper Source Type: research