Spleen Angiosarcoma: A World Review

In this study, we aim to provide a comprehensive review of SA.AREAS COVERED: On 27 February 2021, a literature search was done Pubmed and Embase database. The search yielded 122 articles involving 205 patients. The focus was on patient demographics, risk factors, clinical presentations, investigation results, preliminary diagnoses, therapies provided, and patient outcomes. These factors were analyzed to identify possible risk factors, diagnostic modalities, and therapeutic principles that were not mentioned before.EXPERT OPINION: The clinical presentation or investigation results of patients with SA are often non-specific. Hence, they may not be sufficient to clinch the diagnosis of SA if used alone. The authors recommend a triple assessment of clinical examination, imaging findings, and pathology to diagnose SA with high accuracy. Splenectomy should be the mainstay of management, with chemotherapy and radiotherapy considered as adjuncts, especially in the presence of metastases.PMID:34160346 | DOI:10.1080/17474124.2021.1945920
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research