Psychological Distress and Its Association With Quality of Life in Organ Transplant Recipients During COVID-19 Pandemic
Objectives: The coronavirus disease 2019 (COVID-19) pandemic may have an impact on the psychological distress of organ transplant recipients. We aimed to assess the status of psychological distress and its association with quality of life (QoL) in organ transplant recipients during the COVID-19 pandemic.Materials and Methods: A cross-sectional survey was carried out with 305 organ transplant recipients during March 30 and April 2, 2020, in Wuhan. Psychological distress comprised depression, anxiety, insomnia, and post-traumatic stress disorder (PTSD), which were assessed using the Patient Health Questionnaire-9, the seven-item Generalized Anxiety Disorder questionnaire, the Insomnia Severity Index, and Impact of event scale-revised. QoL was assessed using the Chinese version of the short Form 36-item health survey.Results: The prevalence of depression, anxiety, insomnia, and PTSD in organ transplant recipients was 13.4, 6.9, 11.8, and 30.5%, respectively. Organ transplant recipients with depression had significantly lower scores in all eight dimensions of QoL compared with participants without depression (all p
AbstractPurposeGenetic variants may influence the pharmacokinetics and pharmacodynamics (PKPD) of cyclophosphamide (CY). CY plays a critical role in conditioning chemotherapy for hematopoietic cell transplantation (HCT), but its use is limited by toxicity. We explored the effect of genetic variants, potentially affecting PKPD of CY, and outcomes after HCT.MethodsThis observational pharmacogenomic study included 85 adults with hematologic malignancies who received reduced intensity conditioning with CY, fludarabine, and total body irradiation. We collected recipient DNA prior to HCT and evaluated 97 candidate variants in 66...
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Mariana Rodriguez-Hakim, Linard R äz, Jan Vermant Some contagious diseases, such as COVID-19, spread through the transmission of aerosols and droplets. Aerosol and droplet formation occurs inside and outside of the respiratory tract, the latter being observed... The content of this RSS Feed (c) The Royal Society of Chemistry
Abbott Laboratories has distributed more than 1.4 billion Covid-19 tests globally since the start of the pandemic, including around 300 million in the fourth quarter of 2021. Its global Covid-19 testing-related sales were $2.3 billion in the fourth quarter and $7.7 billion for the full year in 2021.
A deep molecular dive into COVID-19 patients found that the presence of autoantibodies in peripheral blood at initial diagnosis was the chief of four risk factors predicting if a patient would experience long COVID.Medscape Medical News
NIH-sponsored study assessed dose in adults fully vaccinated with any EUA or approved COVID-19 vaccine
ConclusionEmphysematous changes and lower levels of plasma irisin were associated with CLAD, especially in patients with BOS, after bilateral LDLLT.
AbstractPurposeTo evaluate the long-term efficacy of large gastric pouch surgery and revisional surgery in patients with a body mass index (BMI)
AbstractPurposesThe spread of coronavirus disease 2019 (COVID-19) has affected socioeconomic and healthcare systems in many countries. Accordingly, many individuals may have canceled their annual health-check programs, including esophagogastroduodenoscopy, which would have resulted in lower numbers of newly diagnosed patients with gastric cancer in comparison to other times.MethodsQuestionnaires were distributed to 62 hospitals every week from May 2020 to August 2020 (total 744) through mailing lists of the Stomach Cancer Study Group of the Japan Clinical Oncology Group. The number of patients with gastric cancer and hospi...
Hi everyone. I'm new to SDN so please be nice A little background: I'm a first year MSW student focusing on psychodynamic clinical social work. During the pandemic I realized that I wanted to go back to school to become a psychotherapist and began the process of looking into gradate school options. Truthfully, I really wanted to do my doctorate in clinical psychology but as this was a slightly later in life realization (I'm in my late 20s) and wasn't a psych undergrad with any... Read more
Medtronic announces FDA approval of spinal cord stimulation therapy for treating chronic pain resulting from diabetic peripheral neuropathy /PRNewswire/ -- Medtronic plc (NYSE:MDT), a global leader in healthcare technology, today announced it has received U.S. Food and Drug Administration approval... www.prnewswire.com "Medtronic estimates that up to 800,000 US patients suffer from moderate to severe DPN symptoms that are not resolved through conventional medical management approaches, like drugs. The company views these patients as potential ...