Niacin Increases Atherogenic Proteins in High-Density Lipoprotein of Statin-Treated Subjects
CONCLUSIONS: The addition of niacin to statin therapy resulted in elevated levels of multiple HDL proteins linked to increased atherosclerotic risk, which might have compromised the cardioprotective effects associated with higher HDL-C levels and lower levels of LDL-C and triglycerides.REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT00715273; NCT00880178; NCT00120289.PMID:34134520 | DOI:10.1161/ATVBAHA.121.316278
Source: Arteriosclerosis, Thrombosis and Vascular Biology - Category: Cardiology Authors: Graziella E Ronsein Tomas Vaisar W Sean Davidson Karin E Bornfeldt Jeffrey L Probstfield Kevin D O'Brien Xue-Qiao Zhao Jay W Heinecke Source Type: research
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