Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma A β42/Aβ40 and p-tau

DISCUSSION: A combination of plasma Aβ42/Aβ40 and p-tau217 discriminated Aβ status with relatively high accuracy, whereas p-tau217 showed strongest associations with Aβ pathology in MCI but not in CU.PMID:34151519 | DOI:10.1002/alz.12395

Source: The Journal of Alzheimers Association - June 21, 2021 Category: Psychiatry Authors: Shorena Janelidze Sebastian Palmqvist Antoine Leuzy Erik Stomrud Inge M W Verberk Henrik Zetterberg Nicholas J Ashton Pedro Pesini Leticia Sarasa Jos é Antonio Allué Charlotte E Teunissen Jeffrey L Dage Kaj Blennow Niklas Mattsson-Carlgren Oskar Hansson Source Type: research