Differential expression of miRNAs and functional role of mir-200a in high and low productivity CHO cells expressing an Fc fusion protein

CONCLUSION: These results may suggest a role for miR-200a in post-transcriptional regulation of the UPR, presenting miR-200a as a potential target for engineering industrially attractive CHO cell phenotypes.PMID:34131805 | DOI:10.1007/s10529-021-03153-7

Source: Biotechnology Letters - June 16, 2021 Category: Biotechnology Authors: Laura Bryan Michael Henry Niall Barron Clair Gallagher Ronan M Kelly Christopher C Frye Matthew D Osborne Martin Clynes Paula Meleady Source Type: research