Association of Differential Leukocyte Count With Incident Abdominal Aortic Aneurysm Over 22.5 Years: The ARIC Study

CONCLUSIONS: Higher neutrophil, monocyte, and eosinophil counts in midlife are associated with higher risk of AAA, even after accounting for traditional risk factors such as smoking, obesity, and atherosclerosis. This suggests the need to identify nontraditional risk factors and treatment strategies to mitigate the residual risk of AAA conferred by midlife inflammation. Whether immunosuppression is associated with higher risk of AAA needs further investigation.PMID:34134517 | DOI:10.1161/ATVBAHA.121.315903

Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 17, 2021 Category: Cardiology Authors: Romil R Parikh Aaron R Folsom Kripa Poudel Pamela L Lutsey Ryan T Demmer James S Pankow Lin Y Chen Weihong Tang Source Type: research