Incidence, Management, and Prognosis of Graft Failure and Autologous Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation

CONCLUSION: Primary GF exhibited high mortality rate. Secondary GF had 4.5% 10-year cumulative incidence, median onset of 3 months after HCT, and showed 5-year Kaplan-Meier survival of 28.8%. Diagnosis of severe AA and use of RIC was both associated with higher incidence and better survival rate in secondary GF group. AR occurred in 11.6% in secondary GF, exhibited excellent prognosis.PMID:34128593 | DOI:10.3346/jkms.2021.36.e151

Source: Journal of Korean Medical Science - June 15, 2021 Category: Biomedical Science Authors: Jun Hong Park Je Hwan Lee Jung Hee Lee Han Seung Park Eun Ji Choi Young Ah Kang Hyeran Kang Ji Min Woo Young Shin Lee Mijin Jeon Kyoo Hyung Lee Source Type: research