Engineered NK cells can eliminate glioblastoma stem cells

(University of Texas M. D. Anderson Cancer Center) Preclinical research finds that glioblastoma stem cells can be targeted by NK cells, but they are able to evade immune attack by releasing TFG-β. Deleting the TFG-β receptor in NK cells renders them resistant to this and restores their anti-tumor activity.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news