GW4 takes a world leading One Health approach to tackling the antimicrobial resistance pandemic

The GW4 Alliance (Bath, Bristol, Cardiff and Exeter universities – GW4) formally launched their new ‘ One Health ’ antimicrobial resistance research consortium this week [Wednesday 16 June]. The World Health Organisation cites antimicrobial resistance (AMR) as one of the most significant risks facing the world. AMR threatens global health and development as it impacts on human, animal and plant health and also our environment, water safety and food security.
Source: University of Bristol news - Category: Universities & Medical Training Tags: Health, Research, International; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Bristol Veterinary School, Faculty of Health Sciences, Population Health Sciences, Faculty of Life Sciences, Schoo Source Type: news

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Publication date: Available online 29 September 2020Source: The LancetAuthor(s): Steffanie A Strathdee, Sally C Davies, Jasmine R Marcelin
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionsOur results illustrate the importance of continued adherence to infection prevention and control measures during the COVID-19 pandemic to prevent VRE transmission and healthcare associated infections.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Dr. Rodney Rohde, a virologist and clinical laboratory expert, explains how the Covid-19 pandemic can make antimicrobial resistance a bigger problem if health systems aren ’t careful.
Source: Healthcare News - Category: Pharmaceuticals Authors: Tags: Healthcare /healthcare Innovation /innovation Editors' Pick editors-pick Coronavirus Source Type: news
An amendment to this paper has been published and can be accessed via the original article.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Abstract Critical care medicine is a medical specialty engaging the diagnosis and treatment of critically ill patients who have or are likely to have life-threatening organ failure. Sepsis, a life-threatening condition that arises when the body responds to infection, is currently the major cause of death in intensive care units (ICU). Although progress has been made in understanding the pathophysiology of sepsis, many drawbacks in sepsis treatment remains unresolved. For example, antimicrobial resistance, controversial of glucocorticoids use, prolonged duration of ICU care and the subsequent high cost of the treat...
Source: The American Journal of Chinese Medicine - Category: Complementary Medicine Authors: Tags: Am J Chin Med Source Type: research
Purpose of review To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of resistance. Recent findings Extended-spectrum and carbapenemase producing Enterobacterales and multidrug and extensive drug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii have increased worldwide. Sequence type (ST)131 Escherichia coli, ST258, ST11, ST10, ST147 and ST307 Klebsiella pneumonia...
Source: Current Opinion in Critical Care - Category: Nursing Tags: SEVERE INFECTIONS: Edited by Jean-Fran├žois Timsit Source Type: research
ConclusionsWith no alternative antimicrobial treatment options for gonorrhoea and only a few new drugs in the development pipeline, it is necessary to monitor drug resistance and optimize treatment regimens regularly. Moreover, investigations for novel drugs should be wired.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
While current research efforts focus primarily on identifying patient level interventions that mitigate the direct impact of COVID-19, it is important to consider the collateral effects of COVID-19 on antimicrobial resistance. Early reports suggest high rates of antibiotic utilization in COVID-19 patients despite their lack of direct activity against viral pathogens. The ongoing pandemic is exacerbating known barriers to optimal antibiotic stewardship in the ED, representing an additional direct threat to patient safety and public health. There is an urgent need for research analyzing overall and COVID-19 specific antibiot...
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research
AbstractCurrently available evidence supports that the predominant route of human-to-human transmission of the SARS-CoV-2 is through respiratory droplets and/or contact routes. The report by the World Health Organization (WHO) Joint Mission on Coronavirus Disease 2019 (COVID-19) in China supports person-to-person droplet and fomite transmission during close unprotected contact with the vast majority of the investigated infection clusters occurring within families, with a household secondary attack rate varying between 3 and 10%, a finding that is not consistent with airborne transmission. The reproduction number (R0) for t...
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Over the past two weeks, the House Appropriations Committee has swiftly advanced all twelve appropriations bills for fiscal year (FY) 2021. These bills will now be considered by the full House of Representatives. The Commerce, Justice, and Science (CJS) spending measure would provide $8.55 billion to the National Science Foundation (NSF), which is $270 million increase from FY 2020. The President proposed a 6 percent cut for the science agency for FY 2021. Research and related activities within NSF, which includes the Biological Sciences Directorate, would receive grow by $230 million to $6.97 billion in FY 2021. Under t...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
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