Impact of the Omics-Based Biomarkers on the Mirtazapine's Steady-State Concentration, Efficacy and Safety in Patients with Affective Disorders Comorbid with Alcohol Use Disorder

CONCLUSION: Thus, the effect of genetic polymorphism of the CYP3A4, CYP2C9, CYP2C9, CYP3A5, ABCB1, CYP2C19, CYP2C19, CYP2C19, SCL6A4, 5-HTR2A gene on the efficacy and safety profiles of mirtazapine was not demonstrated in a group of 108 patients with depressive disorder and alcohol use disorder.PMID:34092821 | PMC:PMC8146558

Source: Psychopharmacology Bulletin - June 7, 2021 Category: Psychiatry & Psychology Authors: M S Zastrozhin VYu Skryabin VYu Smirnov A K Zastrozhina E V Kaverina D A Klepikov E A Grishina K A Ryzhikova I V Bure E A Bryun D A Sychev Source Type: research