Modeling seizures: from single neurons to networks

Epilepsies are defined by the occurrence of spontaneous and recurrent seizures [1]. Seizures are characterized by electrophysiological (field potential) signatures, varying from one patient to the next and even within a given patient [2]. Given such variability, it is important to rely on a taxonomy of seizures, not only for mechanistic studies (different seizures may be associated with different underlying mechanisms, hence to different pharmacotherapy) but also for diagnostic purposes (particularly for presurgical evaluation in the case of drug-resistant epilepsies).

Source: Seizure: European Journal of Epilepsy - June 17, 2021 Category: Neurology Authors: Damien Depannemaecker, Alain Destexhe, Viktor Jirsa, Christophe Bernard Tags: Review Source Type: research