Perineural invasion in oral squamous cell carcinoma: incidence, clinical impact and molecular insight

Perineural invasion (PNI) has been associated with poor prognosis in oral squamous cell carcinoma (OSCC). Nerve growth factor (NGF) and its receptor tyrosine kinase A (TrkA) may play a role in PNI in OSCC.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 17, 2021 Category: ENT & OMF Authors: H Alkhadar, M Macluskey, S White, I Ellis Source Type: research