High-grade Primary Central Nervous System Lymphomatoid Granulomatosis: Successful Rituximab Monotherapy

Intern Med. 2021 Jun 12. doi: 10.2169/internalmedicine.7232-21. Online ahead of print.ABSTRACTThe primary central nervous system (CNS) presentation of lymphomatoid granulomatosis (LYG) is rare, and no standard therapy for LYG with primary CNS symptoms exists. CNS-LYG patients usually survive for only less than a year from diagnosis. This is the first report of high-grade primary CNS-LYG with monoclonality that was successfully treated with rituximab monotherapy, resulting in a durable remission for more than 1year in a 66-year-old woman with pemphigus vulgaris who was also on immunosuppressive therapy.PMID:34121006 | DOI:10.2169/internalmedicine.7232-21

Source: Internal Medicine - June 14, 2021 Category: Internal Medicine Authors: Sakiko Harada Jun Ando Miki Ando Hideaki Nitta Tadaaki Inano Yusuke Hirasawa Yoshiki Furukawa Shintaro Kinoshita Akihide Kondo Koichi Ohshima Norio Komatsu Source Type: research