Effect of Ultrashort-Acting β-Blockers on Mortality in Patients With Sepsis With Persistent Tachycardia Despite Initial Resuscitation: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Review of 7 RCTs (n=613) reported significantly lower 28-day mortality with ultra-short acting β-blockers esmolol and landiolol vs placebo/no-intervention in patients with sepsis& septic shock (RR 0.68, 95% CI 0.54-0.85). Absolute risk reduction was 18.2% and NNT was 5.5.

Source: Current Awareness Service for Health (CASH) - June 16, 2021 Category: Consumer Health News Source Type: news