Incidence and risk factors of late-onset hemorrhagic cystitis after single umbilical cord blood transplantation with myeloablative conditioning regimen

CONCLUSION: Patients with less well-matched grafts have a higher incidence of LOHC. Inherent deficiencies in immunity in the context of HLA disparity and more intense pharmacologic immunosuppression after severe acute graft-versus-host disease may contribute to viral activation. Prevention and treatment of LOHC have the potential to prolong long-term survival.PMID:34117990 | DOI:10.1007/s12185-021-03168-w

Source: International Journal of Hematology - June 12, 2021 Category: Hematology Authors: Huimin Jiang Liangquan Geng Xiang Wan Kaidi Song Juan Tong Xiaoyu Zhu Baolin Tang Wen Yao Xuhan Zhang Guangyu Sun Lei Zhang Zimin Sun Huilan Liu Source Type: research