Pilot randomized placebo-controlled clinical trial of high-dose gabapentin for alcohol use disorder

CONCLUSIONS: Gabapentin treatment rapidly titrated to a dose of 3600 mg per day is associated with a reduction in the proportion of HDD per week and an increase in PDA per week in actively drinking outpatients with AUD. High-dose gabapentin is potentially a feasible approach to treating AUD and deserving of further study.PMID:34120336 | DOI:10.1111/acer.14648

Source: Alcoholism, Clinical and Experimental Research - June 13, 2021 Category: Addiction Authors: John J Mariani Martina Pavlicova Cale Basaraba Agnieszka Mamczur-Fuller Daniel J Brooks Adam Bisaga Kenneth M Carpenter Edward Nunes Frances R Levin Source Type: research