Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: < em > in vivo < /em > investigations with mass spectrometry imaging

In conclusion, AFL and NI result in distinct cutaneous biodistribution patterns and pharmacokinetic profiles for BLM applied to in vivo skin. Evaluation of LSRs showed that both methods were similarly tolerable, and each method has potential for individualized approaches in a clinical setting.PMID:34121567 | DOI:10.1080/10717544.2021.1933649

Source: Drug Delivery - June 14, 2021 Category: Drugs & Pharmacology Authors: Kristoffer Hendel Anders C N Hansen Liora Bik Charlotte Bagger Martijn B A van Doorn Christian Janfelt Uffe H Olesen Merete Haedersdal Catharina M Lerche Source Type: research