Family History Doubles Asthma Risk for Preschoolers
Rates for boys decline with age but stay steady among girls; rates higher among Black versus non - Hispanic White children during preschool years
It is estimated that more than 90% of children presenting to the emergency department (ED) with a parent-reported penicillin (PCN) allergy do not have true allergy;1 however, non-immunoglobulin E (IgE) mediated side effects often cannot be differentiated from true allergic reaction.1,2 “Delabeling” methods have been proposed to address misclassified PCN allergies and promote antimicrobial stewardship, optimize outcomes, and reduce costs.3 An oral PCN challenge with a single or graded two-dose is the gold standard and most rapid method for delabeling low-risk patients.
Our objective was to review the literature related to Mountain cedar in terms of allergic disease and societal impact.
Infection with COVID-19 has led to over 4 million deaths worldwide, challenging our healthcare systems. At the same time, it has also led to an increased use of non-pharmaceutical interventions (NPIs) to minimize disease spread. COVID-era NPIs such as physical distancing are associated with an unprecedented decrease of non-COVID-19 viral respiratory diseases.1-3
Large study of Hispanic adults shows association with risk for chronic obstructive pulmonary disease before age 50
CONCLUSION: There is growing understanding and recognition of the myriad of ways in which social media is impacting health care. Healthcare professionals from all backgrounds need to increase their understanding of these complex interactions in order to best assist patients with their medical decision making.PMID:34555532 | DOI:10.1016/j.anai.2021.09.014
Chem Asian J. 2021 Sep 22. doi: 10.1002/asia.202100896. Online ahead of print.ABSTRACTInterleukin-33 (IL-33) is an epithelial-derived cytokine that plays an important role in immune-mediated diseases such as asthma, atopic dermatitis, and rheumatoid arthritis. Although IL-33 is considered a potential target for the treatment of allergy-related diseases, no small molecule that inhibits IL-33 has been reported. Based on the structure-activity relationship and in vitro 2D NMR studies employing 15 N-labeled IL-33, we identified that the oxazolo[4,5- c ]-quinolinone analog 7c binds to the interface region of IL-33 and IL-33 rec...
As my sixteen year tenure as Editor-in-chief of the Annals of Allergy Asthma and Immunology draws to a close, I am reflecting on the challenges, victories and failures that have occurred that shaped the journal and the impact they had on me personally. Looking back, I can think of no greater impact on this process than the privilege I had to know and work with my editorial predecessor, Edward J. O'Connell, MD . To know Ed was to love and respect him. If he knew this tome was going to be published as a “Giants in Allergy-Immunology” feature, I strongly suspect he would blush and protest that he was no giant &nda...
It comes as no surprise that the delivery and payment for healthcare services in the United States is constantly changing. Recently, the federal government through the Centers for Medicare and Medicaid Services Innovation (CMMI) was instructed to work toward value-based healthcare delivery models.1 CMMI was developed to address these challenges through creativity and innovation.2 The allergy-immunology specialty is small (less than 6,000 physicians), but our perspective of our nation's healthcare delivery system may be instructive for all of medicine as we adapt to these and other disruptive changes in healthcare.