Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study

by Hyun Ho Jo, Changwook Min, Dae-Sung Kyoung, Min-Ae Park, Sang Gyune Kim, Young Seok Kim, Young Chang, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Baek Gyu Jun, Young Don Kim, Gab Jin Cheon, Jeong-Ju Yoo BackgroundPatients with liver cirrhosis have an increased risk of in-hospital mortality or postoperative complication after surgery. However, large-scale studies on the prognosis of these patients after surgery are lacking. The aim of the study was to investigate the adverse outcomes of patients with liver cirrhosis after surgery over five years. Methods and findingsWe used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwent surgery, 16,174 (1.0%) patients had cirrhosis. The in-hospital mortality (8.0% vs. 1.0%) and postoperative complications such as respiratory (6.0% vs. 5.3%) or infections (2.8% vs. 2.4%) was significantly higher in patients with cirrhosis than in those without cirrhosis. In addition, the total hospitalization period and use of the intensive care unit were significantly higher in patients with liver cirrhosis. In propensity score matching analysis, liver cirrhosis increased the risk of adverse outcome significantly [adjusted OR (aOR) 1.67, 95% CI 1.56 –1.79, P
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research