Cystic fibrosis-related diabetes (CFRD) and cognitive function in adults with cystic fibrosis

Cystic fibrosis-related diabetes (CFRD) is an important and well-established complication of cystic fibrosis (CF), affecting up to 50% of patients by the third decade of life [1]. This unique form of diabetes occurs most commonly in those with severe CF mutations, increases with age, and results from anatomical and functional pancreatic abnormalities as well as defective CFTR function within the pancreatic β cells [2–4]. CFRD is neither Type 1 (T1DM) nor Type 2 diabetes mellitus (T2DM), but shares clinical characteristics of both [4].

Source: Journal of Cystic Fibrosis - June 13, 2021 Category: Respiratory Medicine Authors: Helen K Chadwick, Janice Abbott, Margaret Anne Hurley, Louise Dye, Clare L Lawton, Michael W Mansfield, Daniel Peckham Source Type: research