The prognostic significance of Flap Endonuclease 1 (FEN1) in breast ductal carcinoma in situ

ConclusionHigh FEN1 expression is linked to features of aggressive tumour behaviour and may play a role in the direct progression of DCIS to invasive disease. Further studies are warranted to evaluate its mechanistic roles in DCIS progression and prognosis.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research