Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network

CONCLUSIONS: We report EGCG, a green tea polyphenol, as a modulator of in vitro methylglyoxal-induced Tau glycation and its impact on reducing advanced glycation end products in neuroblastoma cells. We unravel unprecedented function of EGCG in remodeling neuronal cytoskeletal integrity.PMID:34084282 | PMC:PMC8169072 | DOI:10.18632/oncotarget.27963

Source: Oncotarget - June 4, 2021 Category: Cancer & Oncology Authors: Shweta Kishor Sonawane Subashchandrabose Chinnathambi Source Type: research